Indie director Jim Jarmusch has forged his reputation on intimate and immaculately cool character-driven dramas like Dead Man, Broken Flowers, Only Lovers Left Alive, and the unconventional zombie dramedy The Dead Don't Die. He has a way of taking famous actors and transforming them in ways we've never seen before. So frankly, we were giddy about this combination of ensemble cast and Jarmusch before we even got to the plot.*
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The identification of ‘boosters’ that drive gene overexpression directly in a CAR construct provides a simple and scalable strategy for developing effective CAR-NK cell therapies for solid tumours.